Enantioselective protonation of alkenyl trifluoroacetates catalyzed by chiral tin methoxide.
نویسندگان
چکیده
Go catalytic! A catalytic enantioselective protonation of alkenyl trifluoroacetates was achieved by using an in situ generated chiral tin bromide methoxide as the chiral catalyst in the presence of methanol. Optically active ketones containing a tertiary stereogenic center at the α-position were obtained with enantioselectivities of up to 94 % ee.
منابع مشابه
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ورودعنوان ژورنال:
- Chemistry
دوره 19 48 شماره
صفحات -
تاریخ انتشار 2013